Regulation of Ion conduction and Assembly of Potassium Channels
Specificity and Assembly of TGF-beta ligand and receptor complexes
expression Methods for EUKARYOTIC membrane proteins and Structure-guided Drug Discovery
Our research goal deals with problems related to protein assembly and molecular recognition in biology,
currently focussed on molecular workings of potassium channels and transmembrane signaling receptors of
TGFbeta superfamily.
Major experimental tools are x-ray crystallography and NMR spectroscopy, combined with site-specific
mutagenesis and protein chemistry to probe underlying mechanisms at molecular level.
Structural Biology Laboratory
The Salk Institute
10010 North Torrey Pines Rd.
La Jolla, CA 92037
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